Anti-ITPKC Antibody Picoband® Fluoro594 Conjugated
Product Specifications
Background
This gene encodes a member of the inositol 1,4,5-trisphosphate [Ins (1,4,5) P (3) ] 3-kinase family of enzymes that catalyze the phosphorylation of inositol 1,4,5-trisphosphate to 1,3,4,5-tetrakisphosphate. The encoded protein is localized to the nucleus and cytoplasm and has both nuclear import and nuclear export activity. Single nucleotide polymorphisms in this gene are associated with Kawasaki disease.
Gene Name
ITPKC
Gene ID
80271
UniProt
Q96DU7
Host
Rabbit
Reactivity
Human
Immunogen
E.coli-derived human ITPKC recombinant protein (Position: D292-E607) . Human ITPKC shares 88.1% and 88% amino acid (aa) sequence identity with mouse and rat ITPKC, respectively.
Clonality
Polyclonal
Applications
Flow Cytometry
Purification
Immunogen affinity purified.
Form
Liquid
References & Citations
1. Chi, H., Huang, F.-Y., Chen, M.-R., Chiu, N.-C., Lee, H.-C., Lin, S.-P., Chen, W.-F., Lin, C.-L., Chan, H.-W., Liu, H.-F., Huang, L.-M., Lee, Y.-J. ITPKC gene SNP rs28493229 and Kawasaki disease in Taiwanese children. Hum. Molec. Genet. 19: 1147-1151, 2010. 2. Dewaste, V., Pouillon, V., Moreau, C., Shears, S., Takazawa, K., Erneux, C. Cloning and expression of a cDNA encoding human inositol 1,4,5-trisphosphate 3-kinase C. Biochem. J. 352: 343-351, 2000. 3. Hamosh, A. Personal Communication. Baltimore, Md. 5/6/2020.
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
Calculated Molecular Weight
75 kDa
Applications Notes
6
Isotype
IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
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