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Anti-GLYAT Antibody Picoband® Fluoro488 Conjugated

Product Specifications

Background

Glycine-N-acyltransferase, also known as GLYAT, is an enzyme which in humans is encoded by the GLYAT gene. The glycine-N-acyltransferase protein conjugates glycine with acyl-CoA substrates in the mitochondria. The protein is thought to be important in the detoxification of endogenous and xenobiotic acyl-CoA's. Two transcript variants encoding different isoforms have been found for this gene.

Gene Name

GLYAT

Gene ID

10249

UniProt

Q6IB77

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

E.coli-derived human GLYAT recombinant protein (Position: K44-L296) . Human GLYAT shares 70.8% and 73.5% amino acid (aa) sequence identity with mouse and rat GLYAT, respectively.

Clonality

Polyclonal

Applications

Flow Cytometry

Purification

Immunogen affinity purified.

Form

Liquid

References & Citations

1. Matsuo, M., Terai, K., Kameda, N., Matsumoto, A., Kurokawa, Y., Funase, Y., Nishikawa, K., Sugaya, N., Hiruta, N., Kishimoto, T. Designation of enzyme activity of glycine-N-acyltransferase family genes and depression of glycine-N-acyltransferase in human hepatocellular carcinoma. Biochem. Biophys. Res. Commun. 420: 901-906, 2012. 2. Mawal, Y., Paradis, K., Qureshi, I. A. Developmental profile of mitochondrial glycine N-acyltransferase in human liver. J. Pediat. 130: 1003-1007, 1997. 3. Mawal, Y. R., Qureshi, I. A. Purification to homogeneity of mitochondrial acyl CoA:glycine N-acyltransferase from human liver. Biochem. Biophys. Res. Commun. 205: 1373-1379, 1994.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Calculated Molecular Weight

34 kDa

Applications Notes

6

Isotype

IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

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