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Anti-GIPC3 Antibody Picoband® Fluoro647 Conjugated

Selected Variant

A12674-2-Fluoro647

Size: 100 µg/Vial

Product Specifications

Background

PDZ domain-containing protein GIPC3 is a protein that in humans is encoded by the GIPC3 gene. The protein encoded by this gene belongs to the GIPC family. Studies in mice suggest that this gene is required for postnatal maturation of the hair bundle and long-term survival of hair cells and spiral ganglion in the ear. Mutations in this gene are associated with autosomal recessive deafness.

Gene Name

GIPC3

Gene ID

126326

UniProt

Q8TF64

Host

Rabbit

Reactivity

Human, Rat

Immunogen

E.coli-derived human GIPC3 recombinant protein (Position: H45-G312) . Human GIPC3 shares 91.8% amino acid (aa) sequence identity with mouse GIPC3.

Clonality

Polyclonal

Applications

Flow Cytometry

Purification

Immunogen affinity purified.

Form

Liquid

References & Citations

1. Ain, Q., Nazli, S., Riazuddin, S., Jaleel, A., Riazuddin, S. A., Zafar, A. U., Khan, S. N., Husnain, T., Griffith, A. J., Ahmed, Z. M., Friedman, T. B., Riazuddin, S. The autosomal recessive nonsyndromic deafness locus DFNB72 is located on chromosome 19p13.3. Hum. Genet. 122: 445-450, 2007. 2. Charizopoulou, N., Lelli, A., Schraders, M., Ray, K., Hildebrand, M. S., Ramesh, A., Srisailapathy, C. R., Oostrik, J., Admiraal, R. J. C., Neely, H. R., Latoche, J. R., Smith, R. J. H., Northup, J. K., Kremer, H., Holt, J. R., Noben-Trauth, K. Gipc3 mutations associated with audiogenic seizures and sensorineural hearing loss in mouse and human. Nature Commun. 2: 201, 2011. Note: Electronic Article. 3. Chen, A., Wayne, S., Bell, A., Ramesh, A., Srisailapathy, C. R., Scott, D. A., Sheffield, V. C., Van Hauwe, P., Zbar, R. I., Ashley, J., Lovett, M., Van Camp, G., Smith, R. J. New gene for autosomal recessive non-syndromic hearing loss maps to either chromosome 3q or 19p. Am. J. Med. Genet. 71: 467-471, 1997.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Calculated Molecular Weight

34 kDa

Applications Notes

6

Isotype

IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

Price

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