Anti-PSF2/GINS2 Antibody Picoband® Fluoro488 Conjugated
Product Specifications
Background
DNA replication complex GINS protein PSF2 is a protein that in humans is encoded by the GINS2 gene. The yeast heterotetrameric GINS complex is made up of Sld5 (GINS4; MIM 610611), Psf1 (GINS1; MIM 610608), Psf2, and Psf3 (GINS3; MIM 610610) . The formation of this complex is essential for the initiation of DNA replication in yeast and Xenopus egg extracts (Ueno et al., 2005 [PubMed 16287864]) . See GINS1 for additional information about the GINS complex.
Gene Name
GINS2
Gene ID
51659
UniProt
Q9Y248
Host
Rabbit
Reactivity
Human
Immunogen
E.coli-derived human PSF2/GINS2 recombinant protein (Position: M1-F185) . Human GINS2 shares 92.4% amino acid (aa) sequence identity with mouse GINS2.
Clonality
Polyclonal
Applications
Flow Cytometry
Purification
Immunogen affinity purified.
Form
Liquid
References & Citations
1. Takayama, Y., Kamimura, Y., Okawa, M., Muramatsu, S., Sugino, A., Araki, H. GINS, a novel multiprotein complex required for chromosomal DNA replication in budding yeast. Genes Dev. 17: 1153-1165, 2003. 2. Ueno, M., Itoh, M., Kong, L., Sugihara, K., Asano, M., Takakura, N. PSF1 is essential for early embryogenesis in mice. Molec. Cell Biol. 25: 10528-10532, 2005.
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
Calculated Molecular Weight
21 kDa
Applications Notes
6
Isotype
IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
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