Anti-GIMAP1 Antibody Picoband® Fluoro488 Conjugated

This gene encodes a protein belonging to the GTP-binding superfamily and to the immuno-associated nucleotide (IAN) subfamily of nucleotide-binding proteins. In humans, the IAN subfamily genes are located in a cluster at 7q36.1. This gene is thought to be involved in the differentiation of T helper (Th) cells of the Th1 lineage, and the related mouse gene has been shown to be critical for the development of mature B and T lymphocytes. Read-through transcription exists between this gene and the downstream GIMAP5 (GTPase, IMAP family member 5) gene.

1. Stamm, O., Krucken, J., Schmitt-Wrede, H.-P., Benten, W. P. M., Wunderlich, F. Human ortholog to mouse imap38 encoding an ER-localizable G-protein belongs to a gene family clustered on chromosome 7q32-q36. Gene 282: 159-167, 2002.