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Anti-HTATSF1 Antibody Picoband® Fluoro488 Conjugated

Product Specifications

Background

HIV Tat-specific factor 1 is a protein that in humans is encoded by the HTATSF1 gene. The protein encoded by this gene functions as a cofactor for the stimulation of transcriptional elongation by HIV-1 Tat, which binds to the HIV-1 promoter through Tat-TAR interaction. This protein may also serve as a dual-function factor to couple transcription and splicing and to facilitate their reciprocal activation. Alternatively spliced transcript variants have been found for this gene.

Gene Name

HTATSF1

Gene ID

27336

UniProt

O43719

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

E.coli-derived human HTATSF1 recombinant protein (Position: H126-D333) . Human HTATSF1 shares 96.2% amino acid (aa) sequence identity with mouse HTATSF1.

Clonality

Polyclonal

Applications

Flow Cytometry

Purification

Immunogen affinity purified.

Form

Liquid

References & Citations

1. Fong, Y. W., Zhou, Q. Stimulatory effect of splicing factors on transcriptional elongation. Nature 414: 929-933, 2001. 2. Stumpf, A. M. Personal Communication. Baltimore, Md. 10/01/2020. 3. Zhang, Z., Will, C. L., Bertram, K., Dybkov, O., Hartmuth, K., Agafonov, D. E., Hofele, R., Urlaub, H., Kastner, B., Luhrmann, R., Stark, H. Molecular architecture of the human 17S U2 snRNP. Nature 583: 310-313, 2020.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Applications Notes

6

Isotype

IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

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