Anti-HTATSF1 Antibody Picoband®

HIV Tat-specific factor 1 is a protein that in humans is encoded by the HTATSF1 gene. The protein encoded by this gene functions as a cofactor for the stimulation of transcriptional elongation by HIV-1 Tat, which binds to the HIV-1 promoter through Tat-TAR interaction. This protein may also serve as a dual-function factor to couple transcription and splicing and to facilitate their reciprocal activation. Alternatively spliced transcript variants have been found for this gene.

E.coli-derived human HTATSF1 recombinant protein (Position: H126-D333) . Human HTATSF1 shares 96.2% amino acid (aa) sequence identity with mouse HTATSF1.

1. Fong, Y. W., Zhou, Q. Stimulatory effect of splicing factors on transcriptional elongation. Nature 414: 929-933, 2001. 2. Stumpf, A. M. Personal Communication. Baltimore, Md. 10/01/2020. 3. Zhang, Z., Will, C. L., Bertram, K., Dybkov, O., Hartmuth, K., Agafonov, D. E., Hofele, R., Urlaub, H., Kastner, B., Luhrmann, R., Stark, H. Molecular architecture of the human 17S U2 snRNP. Nature 583: 310-313, 2020.

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.