Anti-HIBADH Antibody Picoband® Fluoro647 Conjugated
Product Specifications
Background
In enzymology, a 3-hydroxyisobutyrate dehydrogenase also known as β-hydroxyisobutyrate dehydrogenase or 3-hydroxyisobutyrate dehydrogenase, mitochondrial (HIBADH) is an enzyme that in humans is encoded by the HIBADH gene. This gene encodes a mitochondrial 3-hydroxyisobutyrate dehydrogenase enzyme. The encoded protein plays a critical role in the catabolism of L-valine by catalyzing the oxidation of 3-hydroxyisobutyrate to methylmalonate semialdehyde.
Gene Name
HIBADH
Gene ID
11112
UniProt
P31937
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
E.coli-derived human HIBADH recombinant protein (Position: R34-E332) . Human HIBADH shares 93.3% and 92.6% amino acid (aa) sequence identity with mouse and rat HIBADH, respectively.
Clonality
Polyclonal
Applications
Flow Cytometry
Purification
Immunogen affinity purified.
Form
Liquid
References & Citations
1. Rougraff, P. M., Zhang, B., Kuntz, M. J., Harris, R. A., Crabb, D. W. Cloning and sequence analysis of a cDNA for 3-hydroxyisobutyrate dehydrogenase: evidence for its evolutionary relationship to other pyridine nucleotide-dependent dehydrogenases. J. Biol. Chem. 264: 5899-5903, 1989.
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
Applications Notes
6
Isotype
IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
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