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Anti-HIBADH Antibody Picoband® Fluoro488 Conjugated

Product Specifications

Background

In enzymology, a 3-hydroxyisobutyrate dehydrogenase also known as β-hydroxyisobutyrate dehydrogenase or 3-hydroxyisobutyrate dehydrogenase, mitochondrial (HIBADH) is an enzyme that in humans is encoded by the HIBADH gene. This gene encodes a mitochondrial 3-hydroxyisobutyrate dehydrogenase enzyme. The encoded protein plays a critical role in the catabolism of L-valine by catalyzing the oxidation of 3-hydroxyisobutyrate to methylmalonate semialdehyde.

Gene Name

HIBADH

Gene ID

11112

UniProt

P31937

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

E.coli-derived human HIBADH recombinant protein (Position: R34-E332) . Human HIBADH shares 93.3% and 92.6% amino acid (aa) sequence identity with mouse and rat HIBADH, respectively.

Clonality

Polyclonal

Applications

Flow Cytometry

Purification

Immunogen affinity purified.

Form

Liquid

References & Citations

1. Rougraff, P. M., Zhang, B., Kuntz, M. J., Harris, R. A., Crabb, D. W. Cloning and sequence analysis of a cDNA for 3-hydroxyisobutyrate dehydrogenase: evidence for its evolutionary relationship to other pyridine nucleotide-dependent dehydrogenases. J. Biol. Chem. 264: 5899-5903, 1989.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Applications Notes

6

Isotype

IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

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