Anti-SOX9 Antibody Picoband® Fluoro594 Conjugated
Product Specifications
Background
Transcription factor SOX-9 is a protein that in humans is encoded by the SOX9 gene. The protein encoded by this gene recognizes the sequence CCTTGAG along with other members of the HMG-box class DNA-binding proteins. It acts during chondrocyte differentiation and, with steroidogenic factor 1, regulates transcription of the anti-Muellerian hormone (AMH) gene. Deficiencies lead to the skeletal malformation syndrome campomelic dysplasia, frequently with sex reversal.
Gene Name
SOX9
Gene ID
6662
UniProt
P48436
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
E.coli-derived human SOX9 recombinant protein (Position: M1-Q496) . Human SOX9 shares 97% and 96% amino acid (aa) sequence identity with mouse and rat SOX9, respectively.
Clonality
Polyclonal
Applications
Flow Cytometry
Purification
Immunogen affinity purified.
Form
Liquid
References & Citations
1. Entrez Gene: SOX9 SRY (sex determining region Y) -box 9 (campomelic dysplasia, autosomal sex-reversal) . 2. De Santa Barbara P, Bonneaud N, Boizet B, Desclozeaux M, Moniot B, Sudbeck P, Scherer G, Poulat F, Berta P (November 1998) . interaction of SRY-related protein SOX9 and steroidogenic factor 1 regulates transcription of the human anti-Müllerian hormone gene. Mol. Cell. Biol. 18 (11) : 6653–65.
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
Applications Notes
6
Isotype
IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
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