Anti-SOX9 Antibody Picoband® Fluoro488 Conjugated

Transcription factor SOX-9 is a protein that in humans is encoded by the SOX9 gene. The protein encoded by this gene recognizes the sequence CCTTGAG along with other members of the HMG-box class DNA-binding proteins. It acts during chondrocyte differentiation and, with steroidogenic factor 1, regulates transcription of the anti-Muellerian hormone (AMH) gene. Deficiencies lead to the skeletal malformation syndrome campomelic dysplasia, frequently with sex reversal.

E.coli-derived human SOX9 recombinant protein (Position: M1-Q496) . Human SOX9 shares 97% and 96% amino acid (aa) sequence identity with mouse and rat SOX9, respectively.

1. Entrez Gene: SOX9 SRY (sex determining region Y) -box 9 (campomelic dysplasia, autosomal sex-reversal) . 2. De Santa Barbara P, Bonneaud N, Boizet B, Desclozeaux M, Moniot B, Sudbeck P, Scherer G, Poulat F, Berta P (November 1998) . interaction of SRY-related protein SOX9 and steroidogenic factor 1 regulates transcription of the human anti-Müllerian hormone gene. Mol. Cell. Biol. 18 (11) : 6653–65.