Anti-IRX1 Antibody Picoband® Fluoro488 Conjugated

Iroquois-class homeodomain protein IRX-1, also known as Iroquois homeobox protein 1, is a protein that in humans is encoded by the IRX1 gene. This gene encodes a member of the Iroquois homeobox protein family. Homeobox genes in this family are involved in pattern formation in the embryo. The gene product has been identified as a tumor suppressor in gastric and head and neck cancers. A pseudogene of this gene is located on chromosome 13.

1. Bosse, A., Zulch, A., Becker, M.-B., Torres, M., Gomez-Skarmeta, J. L., Modolell, J., Gruss, P. Identification of the vertebrate Iroquois homeobox gene family with overlapping expression during early development of the nervous system. Mech. Dev. 69: 169-181, 1997. 2. Lewis, M. T., Ross, S., Strickland, P. A., Snyder, C. J., Daniel, C. W. Regulated expression patterns of IRX-2, an Iroquois-class homeobox gene, in the human breast. Cell Tissue Res. 296: 549-554, 1999. 3. Ogura, K., Matsumoto, K., Kuroiwa, A., Isobe, T., Otoguro, T., Jurecic, V., Baldini, A., Matsuda, Y., Ogura, T. Cloning and chromosome mapping of human and chicken Iroquois (IRX) genes. Cytogenet. Cell Genet. 92: 320-325, 2001.