Anti-MASTL Antibody Picoband® Fluoro594 Conjugated

Product Specifications

Background

This gene encodes a microtubule-associated serine/threonine kinase. Mutations at this locus have been associated with autosomal dominant thrombocytopenia, also known as thrombocytopenia-2. Alternatively spliced transcript variants have been described for this locus.

Gene Name

MASTL

Gene ID

84930

UniProt

Q96GX5

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

E.coli-derived human MASTL recombinant protein (Position: E34-L872) . Human MASTL shares 75.1% amino acid (aa) sequence identity with mouse MASTL.

Clonality

Polyclonal

Applications

Flow Cytometry

Purification

Immunogen affinity purified.

Form

Liquid

References & Citations

1. Di Paola, J., Johnson, J. Thrombocytopenias due to gray platelet syndrome or THC2 mutations. Semin. Thromb. Hemost. 37: 690-697, 2011. 2. Drachman, J. G., Jarvik, G. P., Mehaffey, M. G. Autosomal dominant thrombocytopenia: incomplete megakaryocyte differentiation and linkage to human chromosome 10. Blood 96: 118-125, 2000. 3. Gandhi, M. J., Cummings, C. L., Drachman, J. G. FLJ14813 missense mutation: a candidate for autosomal dominant thrombocytopenia on human chromosome 10. Hum. Hered. 55: 66-70, 2003.