Anti-GART Antibody Picoband® Fluoro488 Conjugated
Product Specifications
Background
Trifunctional purine biosynthetic protein adenosine-3 is an enzyme that in humans is encoded by the GART gene. The protein encoded by this gene is a trifunctional polypeptide. It has phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase activity which is required for de novo purine biosynthesis. This enzyme is highly conserved in vertebrates. Alternative splicing of this gene results in two transcript variants encoding different isoforms.
Gene Name
GART
Gene ID
2618
UniProt
P22102
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
E.coli-derived human GART recombinant protein (Position: E68-E1010) . Human GART shares 86.2% amino acid (aa) sequence identity with mouse GART.
Clonality
Polyclonal
Applications
Flow Cytometry
Purification
Immunogen affinity purified.
Form
Liquid
References & Citations
1. Brodsky, G., Barnes, T., Bleskan, J., Becker, L., Cox, M., Patterson, D. The human GARS-AIRS-GART gene encodes two proteins which are differentially expressed during human brain development and temporally overexpressed in cerebellum of individuals with Down syndrome. Hum. Molec. Genet. 6: 2043-2050, 1997. 2. Chadefaux, B., Allard, D., Rethore, M. O., Raoul, O., Poissonnier, M., Gilgenkrantz, S., Cheruy, C., Jerome, H. Assignment of human phosphoribosylglycinamide synthetase locus to region 21q221. Hum. Genet. 66: 190-192, 1984. 3. Cox, D. R., Goldblatt, D., Epstein, C. J. Chromosomal assignment of mouse PRGS: further evidence for homology between mouse chromosome 16 and human chromosome 21. (Abstract) Am. J. Hum. Genet. 33: 145A only, 1981.
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
Applications Notes
6
Isotype
IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
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