Anti-Galectin-7/LGALS7 Antibody Picoband® Fluoro488 Conjugated

Product Specifications

Background

Galectin-7 is a protein that in humans is encoded by the LGALS7 gene. The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. Differential and in situ hybridization studies indicate that this lectin is specifically expressed in keratinocytes and found mainly in stratified squamous epithelium. A duplicate copy of this gene (GeneID:653499) is found adjacent to, but on the opposite strand on chromosome 19.

Gene Name

LGALS7; LGALS7B

Gene ID

3963

UniProt

P47929

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

E.coli-derived human LGALS7 recombinant protein (Position: M1-F136) . Human Galectin-7/LGALS7 shares 78.7% and 72.8% amino acid (aa) sequence identity with mouse and rat LGALS7, respectively.

Clonality

Polyclonal

Applications

Flow Cytometry

Purification

Immunogen affinity purified.

Form

Liquid

References & Citations

1. Cao, Z., Said, N., Amin, S., Wu, H. K., Bruce, A., Garate, M., Hsu, D. K., Kuwabara, I., Liu, F.-T., Panjwani, N. Galectin-3 and -7, but not galectin-1, play a role in re-epithelialization of wounds. J. Biol. Chem. 277: 42299-42305, 2002. 2. Cao, Z., Said, N., Wu, H. K., Kuwabara, I., Liu, F.-T., Panjwani, N. Galectin-7 as a potential mediator of corneal epithelial cell migration. Arch. Ophthal. 121: 82-86, 2003. 3. Hartz, P. A. Personal Communication. Baltimore, Md. 10/3/2016.