Anti-GAREM1 Antibody Picoband® Fluoro488 Conjugated

Product Specifications

Background

This gene encodes an adaptor protein which functions in the epidermal growth factor (EGF) receptor-mediated signaling pathway. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene Name

GAREM1

Gene ID

64762

UniProt

Q9H706

Host

Rabbit

Reactivity

Human

Immunogen

E.coli-derived human GAREM1 recombinant protein (Position: Q277-E753) . Human GAREM1 shares 86.8% amino acid (aa) sequence identity with mouse GAREM1.

Clonality

Polyclonal

Applications

Flow Cytometry

Purification

Immunogen affinity purified.

Form

Liquid

References & Citations

1. Nishino, T., Matsunaga, R., Konishi, H. Functional relationship between CABIT, SAM and 14-3-3 binding domains of GAREM1 that play a role in its subcellular localization. Biochem. Biophys. Res. Commun. 464: 616-621, 2015. 2. Taniguchi, T., Tanaka, S., Ishii, A., Watanabe, M., Fujitani, N., Sugeo, A., Gotoh, S., Ohta, T., Hiyoshi, M., Matsuzaki, H., Sakai, N., Konishi, H. A brain-specific Grb2-associated regulator of extracellular signal-regulated kinase (Erk) mitogen-activated protein kinase (MAPK) (GAREM) subtype, GAREM2, contributes to neurite outgrowth of neuroblastoma cells by regulating Erk signaling. J. Biol. Chem. 288: 29934-29942, 2013. 3. Tashiro, K., Tsunematsu, T., Okubo, H., Ohta, T., Sano, E., Yamauchi, E., Taniguchi, H., Konishi, H. GAREM, a novel adaptor protein for growth factor receptor-bound protein 2, contributes to cellular transformation through activation of extracellular signal-regulated kinase signaling. J. Biol. Chem. 284: 20206-20214, 2009.