Anti-GALP Antibody Picoband®

This gene encodes a member of the galanin family of neuropeptides. The encoded protein binds galanin receptors 1, 2 and 3 with the highest affinity for galanin receptor 3 and has been implicated in biological processes involving the central nervous system including hypothalamic regulation of metabolism and reproduction. A peptide encoded by a splice variant of this gene, termed alarin, has vasoactive properties, displays antimicrobial activity against E. coli, and may serve as a marker for neuroblastic tumors.

E.coli-derived human GALP recombinant protein (Position: M1-S116) . Human GALP shares 67% and 67.3% amino acid (aa) sequence identity with mouse and rat GALP, respectively.

1. Hartz, P. A. Personal Communication. Baltimore, Md. 8/30/2007. 2. Ohtaki, T., Kumano, S., Ishibashi, Y., Ogi, K., Matsui, H., Harada, M., Kitada, C., Kurokawa, T., Onda, H., Fujino, M. Isolation and cDNA cloning of a novel galanin-like peptide (GALP) from porcine hypothalamus. J. Biol. Chem. 274: 37041-37045, 1999. 3. Santic, R., Schmidhuber, S. M., Lang, R., Rauch, I., Voglas, E., Eberhard, N., Bauer, J. W., Brain, S. D., Kofler, B. Alarin is a vasoactive peptide. Proc. Nat. Acad. Sci. 104: 10217-10222, 2007.

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.