Anti-C7orf30/MALSU1 Antibody Picoband®

MALSU1 is a gene on chromosome 7 in humans that encodes the protein MALSU1. This protein localizes to mitochondria and is probably involved in mitochondrial translation or the biogenesis of the large subunit of the mitochondrial ribosome. C7orf30, also known asMALSU1, is a member ofthe iojap protein family. Itwas predicted to enable ribosomal large subunit binding activity. ItwasInvolved in negative regulation of mitochondrial translation and ribosomal large subunit biogenesis.

E.coli-derived human MALSU1 recombinant protein (Position: A30-E234) . Human C7orf30/MALSU1 shares 74.4% amino acid (aa) sequence identity with mouse MALSU1.

1. Hartz, P. A. Personal Communication. Baltimore, Md. 5/7/2012. 2. Rorbach, J., Gammage, P. A., Minczuk, M. C7orf30 is necessary for biogenesis of the large subunit of the mitochondrial ribosome. Nucleic Acids Res. 40: 4097-4109, 2012. Note: Erratum: Nucleic Acids Res. 44: 992 only, 2016. 3. Wanschers, B. F. J., Szklarczyk, R., Pajak, A., van den Brand, M. A. M., Gloerich, J., Rodenburg, R. J. T., Lightowlers, R. N., Nijtmans, L. G., Huynen, M. A. C7orf30 specifically associates with the large subunit of the mitochondrial ribosome and is involved in translation. Nucleic Acids Res. 40: 4040-4051, 2012.

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.