Anti-NRTN Antibody Picoband® Fluoro488 Conjugated

Neurturin (NRTN) is a protein that is encoded in humans by the NRTN gene. This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. The encoded preproprotein is proteolytically processed to generate the mature protein. This protein signals through the RET receptor tyrosine kinase and a GPI-linked coreceptor, and promotes survival of neuronal populations. A neurturin mutation has been described in a family with Hirschsprung Disease.

E.coli-derived human Neurturin/NRTN recombinant protein (Position: M1-V197) . Human Neurturin/NRTN shares 86.3% amino acid (aa) sequence identity with mouse Neurturin/NRTN.

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