Anti-GAS7 Antibody Picoband®

Growth arrest-specific protein 7 is a protein that in humans is encoded by the GAS7 gene. Growth arrest-specific 7 is expressed primarily in terminally differentiated brain cells and predominantly in mature cerebellar Purkinje neurons. GAS7 plays a putative role in neuronal development. Several transcript variants encoding proteins which vary in the N-terminus have been described.

1. Ju, Y.-T., Chang, A. C. Y., She, B.-R., Tsaur, M.-L., Hwang, H.-M., Chao, C. C.-K., Cohen, S. N., Lin-Chao, S. Gas7: a gene expressed preferentially in growth-arrested fibroblasts and terminally differentiated Purkinje neurons affects neurite formation. Proc. Nat. Acad. Sci. 95: 11423-11428, 1998. 2. Kurtz, A., Zimmer, A. Interspecies fluorescence in situ hybridization further defines synteny homology between mouse chromosome 11 and human chromosome 17. Mammalian Genome 6: 379-380, 1995. 3. Megonigal, M. D., Cheung, N.-K. V., Rappaport, E. F., Nowell, P. C., Wilson, R. B., Jones, D. H., Addya, K., Leonard, D. G. B., Kushner, B. H., Williams, T. M., Lange, B. J., Felix, C. A. Detection of leukemia-associated MLL-GAS7 translocation early during chemotherapy with DNA topoisomerase II inhibitors. Proc. Nat. Acad. Sci. 97: 2814-2819, 2000.

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.