Anti-LPXN Antibody Picoband® Fluoro550 Conjugated
Product Specifications
Background
Leupaxin is a protein that in humans is encoded by the LPXN gene. This gene is mapped to 11q12.1. The product encoded by this gene is preferentially expressed in hematopoietic cells and belongs to the paxillin protein family. Similar to other members of this focal-adhesion-associated adaptor-protein family, it has four leucine-rich LD-motifs in the N-terminus and four LIM domains in the C-terminus. It may function in cell type-specific signaling by associating with PYK2, a member of focal adhesion kinase family. As a substrate for a tyrosine kinase in lymphoid cells, this protein may also function in, and be regulated by, tyrosine kinase activity.
Gene Name
LPXN
Gene ID
9404
UniProt
O60711
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
E.coli-derived human LPXN recombinant protein (Position: E45-H323) . Human LPXN shares 89.5% amino acid (aa) sequence identity with mouse LPXN.
Clonality
Polyclonal
Applications
Flow Cytometry
Purification
Immunogen affinity purified.
Form
Liquid
References & Citations
1. Lipsky, B. P., Beals, C. R., Staunton, D. E. Leupaxin is a novel LIM domain protein that forms a complex with PYK2. J. Biol. Chem. 273: 11709-11713, 1998. 2. Entrez Gene: LPXN leupaxin.
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
Applications Notes
6
Isotype
IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
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