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Anti-LYRM4 Antibody Picoband® Fluoro647 Conjugated

Selected Variant

A09301-1-Fluoro647

Size: 100 µg/Vial

Product Specifications

Background

The protein encoded by this gene is found in both mitochondria and the nucleus, where it binds cysteine desulfurase and helps free inorganic sulfur for Fe/S clusters. Disruption of this gene negatively impacts mitochondrial and cytosolic iron homeostasis.

Gene Name

LYRM4

Gene ID

57128

UniProt

Q9HD34

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

E.coli-derived human LYRM4 recombinant protein (Position: M1-T91) . Human LYRM4 shares 89% amino acid (aa) sequence identity with mouse LYRM4.

Clonality

Polyclonal

Applications

Flow Cytometry

Purification

Immunogen affinity purified.

Form

Liquid

References & Citations

1. Adam, A. C., Bornhovd, C., Prokisch, H., Neupert, W., Hell, K. The Nfs1 interacting protein Isd11 has an essential role in Fe/S cluster biogenesis in mitochondria. EMBO J. 25: 174-183, 2006. 2. Hartz, P. A. Personal Communication. Baltimore, Md. 3/17/2010. 3. Lim, S. C., Friemel, M., Marum, J. E., Tucker, E. J., Bruno, D. L., Riley, L. G., Christodoulou, J., Kirk, E. P., Boneh, A., DeGennaro, C. M., Springer, M., Mootha, V. K., Rouault, T. A., Leimkuhler, S., Thorburn, D. R., Compton, A. G. Mutations in LYRM4, encoding iron-sulfur cluster biogenesis factor ISD11, cause deficiency of multiple respiratory chain complexes. Hum. Molec. Genet. 22: 4460-4473, 2013.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Applications Notes

6

Isotype

IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

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