Anti-JADE1 Antibody Picoband®

JADE1 is a protein that in humans is encoded by the JADE1 gene. PHF17 is a component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activitytoward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo.

E.coli-derived human PHF17/JADE1 recombinant protein (Position: I93-D811) . Human PHF17/JADE1 shares 91.5% amino acid (aa) sequence identity with mouse PHF17/JADE1.

1. Nagase, T., Nakayama, M., Nakajima, D., Kikuno, R., Ohara, O. Prediction of the coding sequences of unidentified human genes. XX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. DNA Res. 8: 85-95, 2001. 2. Panchenko, M. V., Zhou, M. I., Cohen, H. T. von Hippel-Lindau partner Jade-1 is a transcriptional co-activator associated with histone acetyltransferase activity. J. Biol. Chem. 279: 56032-56041, 2004. 3. Tzouanacou, E., Tweedie, S., Wilson, V. Identification of Jade1, a gene encoding a PHD zinc finger protein, in a gene trap mutagenesis screen for genes involved in anteroposterior axis development. Molec. Cell Biol. 23: 8553-8562, 2003.

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.