Anti-LY6D Antibody Picoband®

LY6D, also named as E48 and ThB, may act as a specification marker at earliest stage specification of lymphocytes between B- and T-cell development. It marks the earliest stage of B-cell specification.

1. Brakenhoff, R. H., Gerretsen, M., Knippels, E. M. C., van Dijk, M., van Essen, H., Weghuis, D. O., Sinke, R. J., Snow, G. B., van Dongen, G. A. M. S. The human E48 antigen, highly homologous to the murine Ly-6 antigen ThB, is a GPI-anchored molecule apparently involved in keratinocyte cell-cell adhesion. J. Cell Biol. 129: 1677-1689, 1995. 2. Brakenhoff, R. H., van Dijk, M., Rood-Knippels, E. M. C., Snow, G. B. A gain of novel tissue specificity in the human Ly-6 gene E48. J. Immun. 159: 4879-4886, 1997. 3. Inlay, M. A., Bhattacharya, D., Sahoo, D., Serwold, T., Seita, J., Karsunky, H., Plevritis, S. K., Dill, D. L., Weissman, I. L. Ly6d marks the earliest stage of B-cell specification and identifies the branchpoint between B-cell and T-cell development. Genes Dev. 23: 2376-2381, 2009. Note: Erratum: Genes Dev. 27: 2063 only, 2013.

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.