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Anti-LINGO2 Antibody Picoband® Fluoro488 Conjugated

Product Specifications

Background

Leucine rich repeat and Ig domain containing 2 is a protein that in humans is encoded by the LINGO2 gene. LINGO-2 (LRR and Ig domain-containing, Nogo Receptor-interacting protein 2; also LRRN6C and LERN3), is a member of the LRR transmembrane (TM) protein family. LINGO-2 is thought to function outside the CNS with little involvement by p75/NgR1. The human LINGO-2 precursor is a 606 amino acid (aa) type I TM protein that contains a large extracellular domain and a short cytoplasmic tail. The human LINGO-2 precursor is 99% and 98% aa identical to dog and mouse LINGO-2, respectively.

Gene Name

LINGO2

Gene ID

158038

UniProt

Q7L985

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

E.coli-derived human LINGO2 recombinant protein (Position: C28-R513) . Human LINGO2 shares 97.9% amino acid (aa) sequence identity with mouse LINGO2.

Clonality

Polyclonal

Applications

Flow Cytometry

Purification

Immunogen affinity purified.

Form

Liquid

References & Citations

1. Carim-Todd, L., Escarceller, M., Estivill, X., Sumoy, L. LRRN6A/LERN1 (leucine-rich repeat neuronal protein 1), a novel gene with enriched expression in limbic system and neocortex. Europ. J. Neurosci. 18: 3167-3182, 2003.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Applications Notes

6

Isotype

IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

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