Anti-LGALS3 Antibody Picoband® Fluoro488 Conjugated

Galectin-3 (GAL3), also known as LGALS3, MAC2 or GALBP, is a member of the lectin family, of which 14 mammalian galectins have been identified. Galectin-3 is encoded by a single gene, it located on chromosome 14, locus q21–q22. It is expressed in the nucleus, cytoplasm, mitochondrion, cell surface, and extracellular space. Studies have also shown that the expression of galectin-3 is implicated in a variety of processes associated with heart failure, including myofibroblast proliferation, fibrogenesis, tissue repair, inflammation, and Ventricular remodeling. Galectin-3 is expressed in various tissues and organs, but is significantly absent in normal hepatocytes.

E.coli-derived human Galectin-3/LGALS3 recombinant protein (Position: R129-I250) . Human Galectin-3/LGALS3 shares 87.7% and 84.4% amino acid (aa) sequence identity with mouse and rat Galectin-3/LGALS3, respectively.

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