Anti-MICAL3 Antibody Picoband® Fluoro647 Conjugated

Microtubule-associated monoxygenase, calponin and LIM domain containing 3, also known as MICAL3, is a human gene. MICAL3 (microtubule associated monoxygenase, calponin and LIM domain containing 3), also known as KIAA1364, is a 976 amino acid protein that localizes to both the cytoplasm and the cytoskeleton and contains one LIM zinc-binding domain and one calponin-homology domain. Expressed ubiquitously, MICAL3 uses FAD as a cofactor to interact with Rab 1B and, via this interaction, is thought to play a role in spermatid development. MICAL3 exists as two alternatively spliced isoforms that are encoded by a gene which maps to human chromosome 22q11.21. Chromosome 22 houses over 500 genes, some of which are involved in Phelan-McDermid syndrome, schizophrenia and Neurofibromatosis type 2.

E.coli-derived human MICAL3 recombinant protein (Position: K458-L1592) . Human MICAL3 shares 81.9% amino acid (aa) sequence identity with mouse MICAL3.

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