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Anti-MED28 Antibody Picoband® Fluoro488 Conjugated

Product Specifications

Background

Mediator of RNA polymerase II transcription subunit 28 is an enzyme that in humans is encoded by the MED28 gene. MED28 is a component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNApolymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatoryproteins to the basal RNA polymerase.

Gene Name

MED28

Gene ID

80306

UniProt

Q9H204

Host

Rabbit

Reactivity

Human

Immunogen

E.coli-derived human MED28 recombinant protein (Position: M1-T178) . Human MED28 shares 94.4% and 94.9% amino acid (aa) sequence identity with mouse and rat MED28, respectively.

Clonality

Polyclonal

Applications

Flow Cytometry

Purification

Immunogen affinity purified.

Form

Liquid

References & Citations

1. Brass, A. L., Dykxhoorn, D. M., Benita, Y., Yan, N., Engelman, A., Xavier, R. J., Lieberman, J., Elledge, S. J. Identification of host proteins required for HIV infection through a functional genomic screen. Science 319: 921-926, 2008. 2. Liu, C., Zhang, L., Shao, Z.-M., Beatty, P., Sartippour, M., Lane, T. F., Barsky, S. H., Livingston, E., Nguyen, M. Identification of a novel endothelial-derived gene EG-1. Biochem. Biophys. Res. Commun. 290: 602-612, 2002. 3. Lu, M., Zhang, L., Maul, R. S., Sartippour, M. R., Norris, A., Whitelegge, J., Rao, J. Y., Brooks, M. N. The novel gene EG-1 stimulates cellular proliferation. Cancer Res. 65: 6159-6166, 2005.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Applications Notes

6

Isotype

IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

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