Anti-MED28 Antibody Picoband®

Mediator of RNA polymerase II transcription subunit 28 is an enzyme that in humans is encoded by the MED28 gene. MED28 is a component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNApolymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatoryproteins to the basal RNA polymerase.

E.coli-derived human MED28 recombinant protein (Position: M1-T178) . Human MED28 shares 94.4% and 94.9% amino acid (aa) sequence identity with mouse and rat MED28, respectively.

1. Brass, A. L., Dykxhoorn, D. M., Benita, Y., Yan, N., Engelman, A., Xavier, R. J., Lieberman, J., Elledge, S. J. Identification of host proteins required for HIV infection through a functional genomic screen. Science 319: 921-926, 2008. 2. Liu, C., Zhang, L., Shao, Z.-M., Beatty, P., Sartippour, M., Lane, T. F., Barsky, S. H., Livingston, E., Nguyen, M. Identification of a novel endothelial-derived gene EG-1. Biochem. Biophys. Res. Commun. 290: 602-612, 2002. 3. Lu, M., Zhang, L., Maul, R. S., Sartippour, M. R., Norris, A., Whitelegge, J., Rao, J. Y., Brooks, M. N. The novel gene EG-1 stimulates cellular proliferation. Cancer Res. 65: 6159-6166, 2005.

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.