Anti-MELTF Antibody Picoband® Fluoro488 Conjugated

The protein encoded by this gene is a cell-surface glycoprotein found on melanoma cells. The protein shares sequence similarity and iron-binding properties with members of the transferrin superfamily. The importance of the iron binding function has not yet been identified. This gene resides in the same region of chromosome 3 as members of the transferrin superfamily. Alternative splicing results in two transcript variants.

E.coli-derived human MFI2/MELTF recombinant protein (Position: A60-D647) . Human MFI2/MELTF shares 86.7% amino acid (aa) sequence identity with mouse MFI2/MELTF.

1. Le Beau, M. M., Diaz, M. O., Plowman, G. D., Brown, J. P., Rowley, J. D. Chromosomal sublocalization of the human p97 melanoma antigen. Hum. Genet. 72: 294-296, 1986. 2. Plowman, G. D., Brown, J. P., Enns, C. A., Schroder, J., Nikinmaa, B., Sussman, H. H., Hellstrom, K. E., Hellstrom, I. Assignment of the gene for human melanoma-associated antigen p97 to chromosome 3. Nature 303: 70-72, 1983. 3. Rose, T. M., Plowman, G. D., Teplow, D. B., Dreyer, W. J., Hellstrom, K. E., Brown, J. P. Primary structure of the human melanoma-associated antigen p97 (melanotransferrin) deduced from the mRNA sequence. Proc. Nat. Acad. Sci. 83: 1261-1265, 1986.