Anti-PLCB1 Antibody Picoband® Fluoro488 Conjugated
Product Specifications
Background
PLCB1 is also known as PLC-I, EIEE12 or PLC154. The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of many extracellular signals. This gene is activated by two G-protein alpha subunits, alpha-q and alpha-11. Two transcript variants encoding different isoforms have been found for this gene.
Gene Name
PLCB1
Gene ID
23236
UniProt
Q9NQ66
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
E.coli-derived human PLCB1 recombinant protein (Position: H9-D834) . Human PLCB1 shares 98.8% and 98.5% amino acid (aa) sequence identity with mouse and rat PLCB1, respectively.
Clonality
Polyclonal
Applications
Flow Cytometry
Purification
Immunogen affinity purified.
Form
Liquid
References & Citations
1. Guo Y, et al. A loss in cellular protein partners promotes α-synuclein aggregation in cells resulting from oxidative stress. Biochemistry, 2013 Jun 4. 2. Ngoh A, et al. Severe infantile epileptic encephalopathy due to mutations in PLCB1: expansion of the genotypic and phenotypic disease spectrum. Dev Med Child Neurol, 2014 Nov. 3. Philip F, et al. Role of phospholipase C-β in RNA interference. Adv Biol Regul, 2013 Sep.
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
Applications Notes
6
Isotype
IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
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