Anti-PTGER3 Antibody Picoband® Fluoro550 Conjugated

The protein encoded by this gene is a member of the G-protein coupled receptor family. This protein is one of four receptors identified for prostaglandin E2 (PGE2) . This receptor may have many biological functions, which involve digestion, nervous system, kidney reabsorption, and uterine contraction activities. Studies of the mouse counterpart suggest that this receptor may also mediate adrenocorticotropic hormone response as well as fever generation in response to exogenous and endogenous stimuli. Multiple transcript variants encoding different isoforms have been found for this gene.

1. Adam, M., Boie, Y., Rushmore, T. H., Muller, G., Bastien, L., McKee, K. T., Metters, K. M., Abramovitz, M. Cloning and expression of three isoforms of the human EP (3) prostanoid receptor. FEBS Lett. 338: 170-174, 1994. 2. Aronoff, D. M., Lewis, C., Serezani, C. H., Eaton, K. A., Goel, D., Phipps, J. C., Peters-Golden, M., Mancuso, P. E-prostanoid 3 receptor deletion improves pulmonary host defense and protects mice from death in severe Streptococcus pneumoniae infection. J. Immun. 183: 2642-2649, 2009. 3. Duncan, A. M. V., Anderson, L. L., Funk, C. D., Abramovitz, M., Adam, M. Chromosomal localization of the human prostanoid receptor gene family. Genomics 25: 740-742, 1995.