Anti-MBNL3 Antibody Picoband® Fluoro488 Conjugated
Product Specifications
Background
Muscleblind-like protein 3 is a protein that in humans is encoded by the MBNL3 gene. This gene encodes a member of the muscleblind-like family of proteins. The encoded protein may function in regulation of alternative splicing and may play a role in the pathophysiology of myotonic dystrophy. Alternatively spliced transcript variants have been described.
Gene Name
MBNL3
Gene ID
55796
UniProt
Q9NUK0
Host
Rabbit
Reactivity
Human
Immunogen
E.coli-derived human MBNL3 recombinant protein (Position: L106-C312) .
Clonality
Polyclonal
Applications
Flow Cytometry
Purification
Immunogen affinity purified.
Form
Liquid
References & Citations
1. Fardaei, M., Rogers, M. T., Thorpe, H. M., Larkin, K., Hamshere, M. G., Harper, P. S., Brook, J. D. Three proteins, MBNL, MBLL and MBXL, co-localize in vivo with nuclear foci of expanded-repeat transcripts in DM1 and DM2 cells. Hum. Molec. Genet. 11: 805-814, 2002. 2. Hartz, P. A. Personal Communication. Baltimore, Md. 1/11/2012. 3. Ho, T. H., Charlet-B, N., Poulos, M. G., Singh, G., Swanson, M. S., Cooper, T. A. Muscleblind proteins regulate alternative splicing. EMBO J. 23: 3103-3112, 2004.
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
Applications Notes
6
Isotype
IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
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