Anti-NRAP Antibody Picoband® Fluoro594 Conjugated
Product Specifications
Background
NRAP may be involved in anchoring the terminal actin filaments in the myofibril to the membrane and in transmitting tension from the myofibrils to the extracellular matrix.
Gene Name
NRAP
Gene ID
4892
UniProt
Q86VF7
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
E.coli-derived human NRAP recombinant protein (Position: M1-K1513) . Human NRAP shares 86.8% amino acid (aa) sequence identity with mouse NRAP.
Clonality
Polyclonal
Applications
Flow Cytometry
Purification
Immunogen affinity purified.
Form
Liquid
References & Citations
1. Luo, G., Leroy, E., Kozak, C. A., Polymeropoulos, M. H., Horowits, R. Mapping of the gene (NRAP) encoding N-RAP in the mouse and human genomes. Genomics 45: 229-232, 1997. 2. Luo, G., Zhang, J. Q., Nguyen, T.-P., Herrera, A. H., Paterson, B., Horowits, R. Complete cDNA sequence and tissue localization of N-RAP, a novel nebulin-related protein of striated muscle. Cell Motil. Cytoskeleton 38: 75-90, 1997. 3. Truszkowska, G. T., Bilinska, Z. T., Muchowicz, A., Pollak, A., Biernacka, A., Kozar-Kaminska, K., Stawinski, P., Gasperowicz, P., Kosinska, J., Zielinski, T., Ploski, R. Homozygous truncating mutation in NRAP gene identified by whole exome sequencing in a patient with dilated cardiomyopathy. Sci. Rep. 7: 3362, 2017. Note: Electronic Article.
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
Applications Notes
6
Isotype
IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
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