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Anti-NRAP Antibody Picoband® Fluoro488 Conjugated

Product Specifications

Background

NRAP may be involved in anchoring the terminal actin filaments in the myofibril to the membrane and in transmitting tension from the myofibrils to the extracellular matrix.

Gene Name

NRAP

Gene ID

4892

UniProt

Q86VF7

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

E.coli-derived human NRAP recombinant protein (Position: M1-K1513) . Human NRAP shares 86.8% amino acid (aa) sequence identity with mouse NRAP.

Clonality

Polyclonal

Applications

Flow Cytometry

Purification

Immunogen affinity purified.

Form

Liquid

References & Citations

1. Luo, G., Leroy, E., Kozak, C. A., Polymeropoulos, M. H., Horowits, R. Mapping of the gene (NRAP) encoding N-RAP in the mouse and human genomes. Genomics 45: 229-232, 1997. 2. Luo, G., Zhang, J. Q., Nguyen, T.-P., Herrera, A. H., Paterson, B., Horowits, R. Complete cDNA sequence and tissue localization of N-RAP, a novel nebulin-related protein of striated muscle. Cell Motil. Cytoskeleton 38: 75-90, 1997. 3. Truszkowska, G. T., Bilinska, Z. T., Muchowicz, A., Pollak, A., Biernacka, A., Kozar-Kaminska, K., Stawinski, P., Gasperowicz, P., Kosinska, J., Zielinski, T., Ploski, R. Homozygous truncating mutation in NRAP gene identified by whole exome sequencing in a patient with dilated cardiomyopathy. Sci. Rep. 7: 3362, 2017. Note: Electronic Article.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Applications Notes

6

Isotype

IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

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