Anti-POLR1D Antibody Picoband® Fluoro647 Conjugated
Product Specifications
Background
DNA-ed RNA polymerases I and III subunit RPAC2 is a protein that in humans is encoded by the POLR1D gene. The protein encoded by this gene is a component of the RNA polymerase I and RNA polymerase III complexes, which function in the synthesis of ribosomal RNA precursors and small RNAs, respectively. Mutations in this gene are a cause of Treacher Collins syndrome (TCS), a craniofacial development disorder. Alternative splicing results in multiple transcript variants.
Gene Name
POLR1D
Gene ID
51082
UniProt
P0DPB6
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
E.coli-derived human POLR1D recombinant protein (Position: K10-F133) . Human POLR1D shares 90.3% amino acid (aa) sequence identity with mouse POLR1D.
Clonality
Polyclonal
Applications
Flow Cytometry
Purification
Immunogen affinity purified.
Form
Liquid
References & Citations
1. Benedetti, F., Amanzio, M., Rosato, R., Blanchard, C. Nonopioid placebo analgesia is mediated by CB1 cannabinoid receptors. Nature Med. 17: 1228-1230, 2011. 2. Berghuis, P., Dobszay, M. B., Wang, X., Spano, S., Ledda, F., Sousa, K. M., Schulte, G., Ernfors, P., Mackie, K., Paratcha, G., Hurd, Y. L., Harkany, T. Endocannabinoids regulate interneuron migration and morphogenesis by transactivating the TrkB receptor. Proc. Nat. Acad. Sci. 102: 19115-19120, 2005. 3. Berghuis, P., Rajnicek, A. M., Morozov, Y. M., Ross, R. A., Mulder, J., Urban, G. M., Monory, K., Marsicano, G., Matteoli, M., Canty, A., Irving, A. J., Katona, I., Yanagawa, Y., Rakic, P., Lutz, B., Mackie, K., Harkany, T. Hardwiring the brain: endocannabinoids shape neuronal connectivity. Science 316: 1212-1216, 2007.
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
Applications Notes
6
Isotype
IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
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