Anti-POLDIP2 Antibody Picoband®

Polymerase delta-interacting protein 2 also known as Polymerase delta-interacting protein of 38 kDa (PDIP38) is encoded by the POLDIP2 gene in humans. This gene encodes a protein that interacts with the DNA polymerase delta p50 subunit, as well as with proliferating cell nuclear antigen. The encoded protein maybe play a role in the ability of the replication fork to bypass DNA lesions. Alternative splicing results in multiple transcript variants.

E.coli-derived human POLDIP2 recombinant protein (Position: Q81-Q324) . Human POLDIP2 shares 99.2% amino acid (aa) sequence identity with mouse POLDIP2.

1. Klaile, E., Muller, M. M., Kannicht, C., Otto, W., Singer, B. B., Reutter, W., Obrink, B., Lucka, L. The cell adhesion receptor carcinoembryonic antigen-related cell adhesion molecule 1 regulates nucleocytoplasmic trafficking of DNA polymerase delta-interacting protein 38. J. Biol. Chem. 282: 26629-26640, 2007. 2. Liu, L., Rodriguez-Belmonte, E. M., Mazloum, N., Xie, B., Lee, M. Y. W. T. Identification of a novel protein, PDIP38, that interacts with the p50 subunit of DNA polymerase delta and proliferating cell nuclear antigen. J. Biol. Chem. 278: 10041-10047, 2003. 3. Xie, B., Li, H., Wang, Q., Xie, S., Rahmeh, A., Dai, W., Lee, M. Y. W. T. Further characterization of human DNA polymerase delta interacting protein 38. J. Biol. Chem. 280: 22375-22384, 2005.

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.