Anti-POGZ Antibody Picoband® Fluoro550 Conjugated

Product Specifications

Background

Pogo transposable element with ZNF domain is a protein that in humans is encoded by the POGZ gene. The protein encoded by this gene appears to be a zinc finger protein containing a transposase domain at the C-terminus. This protein was found to interact with the transcription factor SP1 in a yeast two-hybrid system. Alternatively spliced transcript variants encoding distinct isoforms have been observed.

Gene Name

POGZ

Gene ID

23126

UniProt

Q7Z3K3

Host

Rabbit

Reactivity

Human

Immunogen

E.coli-derived human POGZ recombinant protein (Position: D23-R1110) . Human POGZ shares 93.7% amino acid (aa) sequence identity with mouse POGZ.

Clonality

Polyclonal

Applications

Flow Cytometry

Purification

Immunogen affinity purified.

Form

Liquid

References & Citations

1. Assia Batzir, N., Posey, J. E., Song, X., Coban Akdemir, Z., Rosenfeld, J. A., Brown, C. W., Chen, E., Holtrop, S. G., Mizerik, E., Nieto Moreno, M., Payne, K., Raas-Rothschild, An., Scott, R., Vernon, H. J., Zadeh, N., Baylor-Hopkins Center for Mendelian Genomics, Lupski, J. R., Reid Suton, V. Phenotypic expansion of POGZ-related intellectual disability syndrome (White-Sutton syndrome) . Am. J. Med. Genet. 182A: 38-52, 2020. 2. Deciphering Developmental Disorders Study. Large-scale discovery of novel genetic causes of developmental disorders. Nature 519: 223-228, 2015. 3. Gunther, M., Laithier, M., Brison, O. A set of proteins interacting with transcription factor Sp1 identified in a two-hybrid screening. Molec. Cell. Biochem. 210: 131-142, 2000.