Anti-POGZ Antibody Picoband®

Pogo transposable element with ZNF domain is a protein that in humans is encoded by the POGZ gene. The protein encoded by this gene appears to be a zinc finger protein containing a transposase domain at the C-terminus. This protein was found to interact with the transcription factor SP1 in a yeast two-hybrid system. Alternatively spliced transcript variants encoding distinct isoforms have been observed.

1. Assia Batzir, N., Posey, J. E., Song, X., Coban Akdemir, Z., Rosenfeld, J. A., Brown, C. W., Chen, E., Holtrop, S. G., Mizerik, E., Nieto Moreno, M., Payne, K., Raas-Rothschild, An., Scott, R., Vernon, H. J., Zadeh, N., Baylor-Hopkins Center for Mendelian Genomics, Lupski, J. R., Reid Suton, V. Phenotypic expansion of POGZ-related intellectual disability syndrome (White-Sutton syndrome) . Am. J. Med. Genet. 182A: 38-52, 2020. 2. Deciphering Developmental Disorders Study. Large-scale discovery of novel genetic causes of developmental disorders. Nature 519: 223-228, 2015. 3. Gunther, M., Laithier, M., Brison, O. A set of proteins interacting with transcription factor Sp1 identified in a two-hybrid screening. Molec. Cell. Biochem. 210: 131-142, 2000.

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.