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Anti-TAS2R10 Antibody Picoband® Fluoro488 Conjugated

Product Specifications

Background

Taste receptor type 2 member 10 is a protein that in humans is encoded by the TAS2R10 gene. This gene product belongs to the family of candidate taste receptors that are members of the G-protein-coupled receptor superfamily. These proteins are specifically expressed in the taste receptor cells of the tongue and palate epithelia. They are organized in the genome in clusters and are genetically linked to loci that influence bitter perception in mice and humans. In functional expression studies, they respond to bitter tastants. This gene maps to the taste receptor gene cluster on chromosome 12p13.

Gene Name

TAS2R10

Gene ID

50839

UniProt

Q9NYW0

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

E.coli-derived human TAS2R10 recombinant protein (Position: E16-T307) .

Clonality

Polyclonal

Applications

Flow Cytometry

Purification

Immunogen affinity purified.

Form

Liquid

References & Citations

1. Adler, E., Hoon, M. A., Mueller, K. L., Chandrashekar, J., Ryba, N. J. P., Zuker, C. S. A novel family of mammalian taste receptors. Cell 100: 693-702, 2000. 2. Chandrashekar, J., Hoon, M. A., Ryba, N. J. P., Zuker, C. S. The receptors and cells for mammalian taste. Nature 444: 288-294, 2006. 3. Deshpande, D. A., Wang, W. C. H., McIlmoyle, E. L., Robinett, K. S., Schillinger, R. M., An, S. S., Sham, J. S. K., Liggett, S. B. Bitter taste receptors on airway smooth muscle bronchodilate by localized calcium signaling and reverse obstruction. Nature Med. 16: 1299-1304, 2010.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Applications Notes

6

Isotype

IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

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