Anti-TAS2R10 Antibody Picoband® Fluoro488 Conjugated
Product Specifications
Background
Taste receptor type 2 member 10 is a protein that in humans is encoded by the TAS2R10 gene. This gene product belongs to the family of candidate taste receptors that are members of the G-protein-coupled receptor superfamily. These proteins are specifically expressed in the taste receptor cells of the tongue and palate epithelia. They are organized in the genome in clusters and are genetically linked to loci that influence bitter perception in mice and humans. In functional expression studies, they respond to bitter tastants. This gene maps to the taste receptor gene cluster on chromosome 12p13.
Gene Name
TAS2R10
Gene ID
50839
UniProt
Q9NYW0
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
E.coli-derived human TAS2R10 recombinant protein (Position: E16-T307) .
Clonality
Polyclonal
Applications
Flow Cytometry
Purification
Immunogen affinity purified.
Form
Liquid
References & Citations
1. Adler, E., Hoon, M. A., Mueller, K. L., Chandrashekar, J., Ryba, N. J. P., Zuker, C. S. A novel family of mammalian taste receptors. Cell 100: 693-702, 2000. 2. Chandrashekar, J., Hoon, M. A., Ryba, N. J. P., Zuker, C. S. The receptors and cells for mammalian taste. Nature 444: 288-294, 2006. 3. Deshpande, D. A., Wang, W. C. H., McIlmoyle, E. L., Robinett, K. S., Schillinger, R. M., An, S. S., Sham, J. S. K., Liggett, S. B. Bitter taste receptors on airway smooth muscle bronchodilate by localized calcium signaling and reverse obstruction. Nature Med. 16: 1299-1304, 2010.
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
Applications Notes
6
Isotype
IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
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