Anti-LARG/ARHGEF12 Antibody Picoband® Fluoro550 Conjugated

Rho guanine nucleotide exchange factor 12 is a protein that in humans is encoded by the ARHGEF12 gene. Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli working through G protein-coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. This protein has been observed to form a myeloid/lymphoid fusion partner in acute myeloid leukemia. Three transcript variants encoding different isoforms have been found for this gene.

E.coli-derived human LARG/ARHGEF12 recombinant protein (Position: D10-E1426) . Human ARHGEF12 shares 89.9% amino acid (aa) sequence identity with mouse ARHGEF12.

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