Anti-ATL1 Antibody Picoband® Fluoro488 Conjugated

Atlastin, or Atlastin-1, is a protein that in humans is encoded by the ATL1 gene. The protein encoded by this gene is a GTPase and a Golgi body transmembrane protein. The encoded protein can form a homotetramer and has been shown to interact with spastin and with mitogen-activated protein kinase kinase kinase kinase 4. This protein may be involved in axonal maintenance as evidenced by the fact that defects in this gene are a cause of spastic paraplegia type 3. Three transcript variants encoding two different isoforms have been found for this gene.

E.coli-derived human ATL1 recombinant protein (Position: E24-Q552) . Human ATL1 shares 97.5% and 98.3% amino acid (aa) sequence identity with mouse and rat ATL1, respectively.

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