Anti-CAPN5 Antibody Picoband® Fluoro647 Conjugated
Product Specifications
Background
Calpain-5 is a protein that in humans is encoded by the CAPN5 gene. Calpains are calcium-dependent cysteine proteases involved in signal transduction in a variety of cellular processes. A functional calpain protein consists of an invariant small subunit and 1 of a family of large subunits. CAPN5 is one of the large subunits. Unlike some of the calpains, CAPN5 and CAPN6 lack a calmodulin-like domain IV. Because of the significant similarity to Caenorhabditis elegans sex determination gene tra-3, CAPN5 is also called as HTRA3.
Gene Name
CAPN5
Gene ID
726
UniProt
O15484
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
E.coli-derived human CAPN5 recombinant protein (Position: N583-N616) . Human CAPN5 shares 84.8% and 78.8% amino acid (aa) sequence identity with mouse and rat CAPN5, respectively.
Clonality
Polyclonal
Applications
Flow Cytometry
Purification
Immunogen affinity purified.
Form
Liquid
References & Citations
1. Bennett, S. R., Folk, J. C., Kimura, A. E., Russell, S. R., Stone, E. M., Raphtis, E. M. Autosomal dominant neovascular inflammatory vitreoretinopathy. Ophthalmology 97: 1125-1135, 1990. 2. Dear, N., Matena, K., Vingron, M., Boehm, T. A new subfamily of vertebrate calpains lacking a calmodulin-like domain: implications for calpain regulation and evolution. Genomics 45: 175-184, 1997. 3. Franz, T., Winckler, L., Boehm, T., Dear, T. N. Capn5 is expressed in a subset of T cells and is dispensable for development. Molec. Cell. Biol. 24: 1649-1654, 2004.
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
Applications Notes
6
Isotype
IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
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