Anti-Pancreatic Lipase/PNLIP Antibody Picoband® Fluoro647 Conjugated

This gene encodes a member of the lipase family of proteins. The encoded enzyme is secreted by the pancreas and hydrolyzes triglycerides in the small intestine, and is essential for the efficient digestion of dietary fats. Inhibition of the encoded enzyme may prevent high-fat diet-induced obesity in mice and result in weight loss in human patients with obesity. Mutations in this gene cause congenital pancreatic lipase deficiency, a rare disorder characterized by steatorrhea.

70 kDa ribosomal protein S6 kinase 1 antibody, KS6B1_HUMAN antibody, p70 alpha antibody, P70 beta 1 antibody, p70 ribosomal S6 kinase alpha antibody, p70 ribosomal S6 kinase beta 1 antibody, p70 S6 kinase alpha antibody, P70 S6 Kinase antibody, p70 S6 kinase alpha 1 antibody, p70 S6 kinase alpha 2 antibody, p70 S6K antibody, p70 S6K-alpha antibody, p70 S6KA antibody, p70 (S6K) alpha antibody, p70 (S6K) -alpha antibody, p70-alpha antibody, p70-S6K 1 antibody, p70-S6K antibody, P70S6K antibody, P70S6K1 antibody, p70S6Kb antibody, PS6K antibody, Ribosomal protein S6 kinase 70kDa polypeptide 1 antibody, Ribosomal protein S6 kinase beta 1 antibody, Ribosomal protein S6 kinase beta-1 antibody, Ribosomal protein S6 kinase I antibody, RPS6KB1 antibody, S6K antibody, S6K-beta-1 antibody, S6K1 antibody, Serine/threonine kinase 14 alpha antibody, Serine/threonine-protein kinase 14A antibody, STK14A antibody

E.coli-derived human Pancreatic Lipase/PNLIP recombinant protein (Position: I36-D404) . Human PNLIP shares 78.7% amino acid (aa) sequence identity with mouse and rat PNLIP.

Downstream effector of TOR signaling pathway involved in osmotic stress response. Could be involved in the control of plant growth and development. Phosphorylates the ribosomal proteins P14, P16 and S6. Functions as a repressor of cell proliferation and required for maintenance of chromosome stability and ploidy levels through the RBR1-E2F pathway.

1. Behar, D. M., Basel-Vanagaite, L., Glaser, F., Kaplan, M., Tzur, S., Magal, N., Eidlitz-Markus, T., Haimi-Cohen, Y., Sarig, G., Bormans, C., Shohat, M., Zeharia, A. Identification of a novel mutation in the PNLIP gene in two brothers with congenital pancreatic lipase deficiency. J. Lipid Res. 55: 307-312, 2014. 2. Davis, R. C., Diep, A., Hunziker, W., Klisak, I., Mohandas, T., Schotz, M. C., Sparkes, R. S., Lusis, A. J. Assignment of human pancreatic lipase gene (PNLIP) to chromosome 10q24-q26. Genomics 11: 1164-1166, 1991. 3. Lowe, M. E., Rosenblum, J. L., Strauss, A. W. Cloning and characterization of human pancreatic lipase cDNA. J. Biol. Chem. 264: 20042-20048, 1989.