Anti-PLEKHB1 Antibody Picoband® Fluoro594 Conjugated

PLEKHB1, also named as Evectin-1, EVT1, KPL1, PHR1 and PHRET1, isrequired for properlocalization of retinogeniculate projections but not for eye-specific segregation. PLEKHB1 has 4 isoforms with MW from 21-27kd. It has Dimerform withMW42-54 kDa.

70 kDa ribosomal protein S6 kinase 1 antibody, KS6B1_HUMAN antibody, p70 alpha antibody, P70 beta 1 antibody, p70 ribosomal S6 kinase alpha antibody, p70 ribosomal S6 kinase beta 1 antibody, p70 S6 kinase alpha antibody, P70 S6 Kinase antibody, p70 S6 kinase alpha 1 antibody, p70 S6 kinase alpha 2 antibody, p70 S6K antibody, p70 S6K-alpha antibody, p70 S6KA antibody, p70 (S6K) alpha antibody, p70 (S6K) -alpha antibody, p70-alpha antibody, p70-S6K 1 antibody, p70-S6K antibody, P70S6K antibody, P70S6K1 antibody, p70S6Kb antibody, PS6K antibody, Ribosomal protein S6 kinase 70kDa polypeptide 1 antibody, Ribosomal protein S6 kinase beta 1 antibody, Ribosomal protein S6 kinase beta-1 antibody, Ribosomal protein S6 kinase I antibody, RPS6KB1 antibody, S6K antibody, S6K-beta-1 antibody, S6K1 antibody, Serine/threonine kinase 14 alpha antibody, Serine/threonine-protein kinase 14A antibody, STK14A antibody

E.coli-derived human PLEKHB1 recombinant protein (Position: H82-S214) . Human PLEKHB1 shares 93.9% and 92.4% amino acid (aa) sequence identity with mouse and rat PLEKHB1, respectively.

Downstream effector of TOR signaling pathway involved in osmotic stress response. Could be involved in the control of plant growth and development. Phosphorylates the ribosomal proteins P14, P16 and S6. Functions as a repressor of cell proliferation and required for maintenance of chromosome stability and ploidy levels through the RBR1-E2F pathway.

1. Andrews, K. L., Potdar, P. D., Nettesheim, P., Ostrowski, L. E. KPL1, which encodes a novel PH domain-containing protein, is induced during ciliated cell differentiation of rat tracheal epithelial cells. Exp. Lung Res. 26: 257-271, 2000. 2. Krappa, R., Nguyen, A., Burrola, P., Deretic, D., Lemke, G. Evectins: vesicular proteins that carry a pleckstrin homology domain and localize to post-Golgi membranes. Proc. Nat. Acad. Sci. 96: 4633-4638, 1999. 3. Xu, S., Ladak, R., Swanson, D. A., Soltyk, A., Sun, H., Ploder, L., Vidgen, D., Duncan, A. M. V., Garami, E., Valle, D., McInnes, R. R. PHR1 encodes an abundant, pleckstrin homology domain-containing integral membrane protein in the photoreceptor outer segments. J. Biol. Chem. 274: 35676-35685, 1999.