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Anti-RBPMS2 Antibody Picoband® Fluoro647 Conjugated

Product Specifications

Background

The protein encoded by this gene is a member of the RNA recognition motif (RRM) -containing protein family and is involved in the development and dedifferentiation of digestive smooth muscle cells. The encoded protein functions as a homodimer and inly inhibits the bone morphogenetic protein pathway.

Synonyms

70 kDa ribosomal protein S6 kinase 1 antibody, KS6B1_HUMAN antibody, p70 alpha antibody, P70 beta 1 antibody, p70 ribosomal S6 kinase alpha antibody, p70 ribosomal S6 kinase beta 1 antibody, p70 S6 kinase alpha antibody, P70 S6 Kinase antibody, p70 S6 kinase alpha 1 antibody, p70 S6 kinase alpha 2 antibody, p70 S6K antibody, p70 S6K-alpha antibody, p70 S6KA antibody, p70 (S6K) alpha antibody, p70 (S6K) -alpha antibody, p70-alpha antibody, p70-S6K 1 antibody, p70-S6K antibody, P70S6K antibody, P70S6K1 antibody, p70S6Kb antibody, PS6K antibody, Ribosomal protein S6 kinase 70kDa polypeptide 1 antibody, Ribosomal protein S6 kinase beta 1 antibody, Ribosomal protein S6 kinase beta-1 antibody, Ribosomal protein S6 kinase I antibody, RPS6KB1 antibody, S6K antibody, S6K-beta-1 antibody, S6K1 antibody, Serine/threonine kinase 14 alpha antibody, Serine/threonine-protein kinase 14A antibody, STK14A antibody

Gene Name

RBPMS2

Gene ID

348093

UniProt

Q6ZRY4

Host

Rabbit

Reactivity

Human

Cross Reactivity

No cross reactivity with other proteins.

Immunogen

E.coli-derived human RBPMS2 recombinant protein (Position: K116-Q201) .

Clonality

Polyclonal

Tissue Specificity

Expressed in all tissues.

Applications

Flow Cytometry

Field of Research

Signal Transduction, Signaling Pathway, Small G Proteins

Purification

Immunogen affinity purified.

Form

Liquid

Function

Downstream effector of TOR signaling pathway involved in osmotic stress response. Could be involved in the control of plant growth and development. Phosphorylates the ribosomal proteins P14, P16 and S6. Functions as a repressor of cell proliferation and required for maintenance of chromosome stability and ploidy levels through the RBR1-E2F pathway.

References & Citations

1. Hapkova, I., Skarda, J., Rouleau, C., Thys, A., Notarnicola, C., Janikova, M., Bernex, F., Rypka, M., Vanderwinden, J.-M., Faure, S., Vesely, J., de Santa Barbara, P. High expression of the RNA-binding protein RBPMS2 in gastrointestinal stromal tumors. Exp. Molec. Path. 94: 314-321, 2013. 2. Notarnicola, C., Rouleau, C., Le Guen, L., Virsolvy, A., Richard, S., Faure, S., de Santa Barbara, P. The RNA-binding protein RBMS2 regulates development of gastrointestinal smooth muscle. Gastroenterology 143: 687-697, 2012. 3. Sagnol, S., Yang, Y., Bessin, Y., Allemand, F., Hapkova, I., Notarnicola, C., Guichou, J.-F., Faure, S., Labesse, G., de Santa Barbara, P. Homodimerization of RBPMS2 through a new RRM-interaction motif is necessary to control smooth muscle plasticity. Nucleic Acids Res. 42: 10173-10184, 2014.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A10660-1-Fluoro647

Calculated Molecular Weight

52588 MW

Applications Notes

6

Gene Name Synonym

Serine/threonine-protein kinase AtPK1/AtPK6

Subcellular Location

Cytoplasm. Nucleus.

Protein Name

Serine/threonine-protein kinase AtPK1/AtPK6

Isotype

IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

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