Anti-SYNPO2 Antibody Picoband® Fluoro647 Conjugated

Myopodin protein, also called Synaptopodin-2 is a protein that in humans is encoded by the SYNPO2 gene. Myopodin is expressed in cardiac, smooth muscle and skeletal muscle, and localizes to Z-disc structures.

70 kDa ribosomal protein S6 kinase 1 antibody, KS6B1_HUMAN antibody, p70 alpha antibody, P70 beta 1 antibody, p70 ribosomal S6 kinase alpha antibody, p70 ribosomal S6 kinase beta 1 antibody, p70 S6 kinase alpha antibody, P70 S6 Kinase antibody, p70 S6 kinase alpha 1 antibody, p70 S6 kinase alpha 2 antibody, p70 S6K antibody, p70 S6K-alpha antibody, p70 S6KA antibody, p70 (S6K) alpha antibody, p70 (S6K) -alpha antibody, p70-alpha antibody, p70-S6K 1 antibody, p70-S6K antibody, P70S6K antibody, P70S6K1 antibody, p70S6Kb antibody, PS6K antibody, Ribosomal protein S6 kinase 70kDa polypeptide 1 antibody, Ribosomal protein S6 kinase beta 1 antibody, Ribosomal protein S6 kinase beta-1 antibody, Ribosomal protein S6 kinase I antibody, RPS6KB1 antibody, S6K antibody, S6K-beta-1 antibody, S6K1 antibody, Serine/threonine kinase 14 alpha antibody, Serine/threonine-protein kinase 14A antibody, STK14A antibody

E.coli-derived human SYNPO2 recombinant protein (Position: L104-R1009) . Human SYNPO2 shares 79.6% and 78.6% amino acid (aa) sequence identity with mouse and rat SYNPO2, respectively.

Downstream effector of TOR signaling pathway involved in osmotic stress response. Could be involved in the control of plant growth and development. Phosphorylates the ribosomal proteins P14, P16 and S6. Functions as a repressor of cell proliferation and required for maintenance of chromosome stability and ploidy levels through the RBR1-E2F pathway.

1. Gao, J., Zhang, H. P., Sun, Y. H., Guo, W. Z., Li, J., Tang, H. W., ... & Zhang, S. J. (2020) . Synaptopodin-2 promotes hepatocellular carcinoma metastasis via calcineurin-induced nuclear-cytoplasmic translocation. Cancer letters, 482, 8-18. 2. Ma, L., Zhang, W., Ding, Z., Wu, S. G., Jin, Y., Jiang, N., ... & Chen, X. (2017) . Association of a common variant of SYNPO2 gene with increased risk of serous epithelial ovarian cancer. Tumor Biology, 39 (2), 1010428317691185. 3. Pompas-Veganzones, N., Sandonis, V., Perez-Lanzac, A., Beltran, M., Beardo, P., Juárez, A., ... & Sanchez-Carbayo, M. (2016) . Myopodin methylation is a prognostic biomarker and predicts antiangiogenic response in advanced kidney cancer. Tumor Biology, 37, 14301-14310.