Anti-SYCN Antibody Picoband® Fluoro550 Conjugated

SYCN functions in exocytosis in pancreatic acinar cells regulating the fusion of zymogen granules with each other. SYCN may have a pore-forming activity on membranes and regulate exocytosis in other exocrine tissues.

70 kDa ribosomal protein S6 kinase 1 antibody, KS6B1_HUMAN antibody, p70 alpha antibody, P70 beta 1 antibody, p70 ribosomal S6 kinase alpha antibody, p70 ribosomal S6 kinase beta 1 antibody, p70 S6 kinase alpha antibody, P70 S6 Kinase antibody, p70 S6 kinase alpha 1 antibody, p70 S6 kinase alpha 2 antibody, p70 S6K antibody, p70 S6K-alpha antibody, p70 S6KA antibody, p70 (S6K) alpha antibody, p70 (S6K) -alpha antibody, p70-alpha antibody, p70-S6K 1 antibody, p70-S6K antibody, P70S6K antibody, P70S6K1 antibody, p70S6Kb antibody, PS6K antibody, Ribosomal protein S6 kinase 70kDa polypeptide 1 antibody, Ribosomal protein S6 kinase beta 1 antibody, Ribosomal protein S6 kinase beta-1 antibody, Ribosomal protein S6 kinase I antibody, RPS6KB1 antibody, S6K antibody, S6K-beta-1 antibody, S6K1 antibody, Serine/threonine kinase 14 alpha antibody, Serine/threonine-protein kinase 14A antibody, STK14A antibody

E.coli-derived human SYCN recombinant protein (Position: A19-S134) . Human SYCN shares 73.9% and 72.2% amino acid (aa) sequence identity with mouse and rat SYCN, respectively.

Downstream effector of TOR signaling pathway involved in osmotic stress response. Could be involved in the control of plant growth and development. Phosphorylates the ribosomal proteins P14, P16 and S6. Functions as a repressor of cell proliferation and required for maintenance of chromosome stability and ploidy levels through the RBR1-E2F pathway.

1. Antonin, W., Wagner, M., Riedel, D., Brose, N., Jahn, R. Loss of the zymogen granule protein syncollin affects pancreatic protein synthesis and transport but not secretion. Molec. Cell. Biol. 22: 1545-1554, 2002. 2. Bach, J. P., Borta, H., Ackermann, W., Faust, F., Borchers, O., Schrader, M. The secretory granule protein syncollin localizes to HL-60 cells and neutrophils. J. Histochem. Cytochem. 54: 877-888, 2006. 3. Edwardson, J. M., An, S., Jahn, R. The secretory granule protein syncollin binds to syntaxin in a Ca2 (+) -sensitive manner. Cell 90: 325-333, 1997.