Anti-STRIP1 Antibody Picoband® Fluoro550 Conjugated
Product Specifications
Background
Protein FAM40A is a protein that is located on chromosome 1 in humans and is encoded by the FAM40A gene. STRIP1 is a core component of striatin-interacting phosphatase and kinase (STRIPAK) complexes, which also include striatins and MST family kinases . STRIPAK complexes appear to regulate the cytoskeleton and cell migration.
Synonyms
70 kDa ribosomal protein S6 kinase 1 antibody, KS6B1_HUMAN antibody, p70 alpha antibody, P70 beta 1 antibody, p70 ribosomal S6 kinase alpha antibody, p70 ribosomal S6 kinase beta 1 antibody, p70 S6 kinase alpha antibody, P70 S6 Kinase antibody, p70 S6 kinase alpha 1 antibody, p70 S6 kinase alpha 2 antibody, p70 S6K antibody, p70 S6K-alpha antibody, p70 S6KA antibody, p70 (S6K) alpha antibody, p70 (S6K) -alpha antibody, p70-alpha antibody, p70-S6K 1 antibody, p70-S6K antibody, P70S6K antibody, P70S6K1 antibody, p70S6Kb antibody, PS6K antibody, Ribosomal protein S6 kinase 70kDa polypeptide 1 antibody, Ribosomal protein S6 kinase beta 1 antibody, Ribosomal protein S6 kinase beta-1 antibody, Ribosomal protein S6 kinase I antibody, RPS6KB1 antibody, S6K antibody, S6K-beta-1 antibody, S6K1 antibody, Serine/threonine kinase 14 alpha antibody, Serine/threonine-protein kinase 14A antibody, STK14A antibody
Gene Name
STRIP1
Gene ID
55342
UniProt
Q5VSL9
Host
Rabbit
Reactivity
Human, Mouse, Rat
Cross Reactivity
No cross reactivity with other proteins.
Immunogen
E.coli-derived human STRIP1 recombinant protein (Position: E93-Q511) . Human STRIP1 shares 98.1% amino acid (aa) sequence identity with mouse STRIP1.
Clonality
Polyclonal
Tissue Specificity
Expressed in all tissues.
Applications
Flow Cytometry
Field of Research
Signal Transduction, Signaling Pathway, Small G Proteins
Purification
Immunogen affinity purified.
Form
Liquid
Function
Downstream effector of TOR signaling pathway involved in osmotic stress response. Could be involved in the control of plant growth and development. Phosphorylates the ribosomal proteins P14, P16 and S6. Functions as a repressor of cell proliferation and required for maintenance of chromosome stability and ploidy levels through the RBR1-E2F pathway.
References & Citations
1. Bazzi, H., Soroka, E., Alcorn, H. L., Anderson, K. V. STRIP1, a core component of STRIPAK complexes, is essential for normal mesoderm migration in the mouse embryo. Proc. Nat. Acad. Sci. 114: E10928-E10936, 2017. Note: Electronic Article. 2. Gross, M. B. Personal Communication. Baltimore, Md. 3/22/2018. 3. Kemp, H. A., Sprague, G. F., Jr. Far3 and five interacting proteins prevent premature recovery from pheromone arrest in the budding yeast Saccharomyces cerevisiae. Molec. Cell. Biol. 23: 1750-1763, 2003
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
Calculated Molecular Weight
96 kDa
Applications Notes
6
Gene Name Synonym
Serine/threonine-protein kinase AtPK1/AtPK6
Subcellular Location
Cytoplasm. Nucleus.
Protein Name
Serine/threonine-protein kinase AtPK1/AtPK6
Isotype
IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
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