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Anti-LMF2 Antibody Picoband® Fluoro647 Conjugated

Product Specifications

Background

LMF2 belongs to the lipase maturation factor family. LMF2 is involved in the maturation of specific proteins in the endoplasmic reticulum. It may be required for maturation and transport of active lipoprotein lipase (LPL) through the secretory pathway.

Synonyms

70 kDa ribosomal protein S6 kinase 1 antibody, KS6B1_HUMAN antibody, p70 alpha antibody, P70 beta 1 antibody, p70 ribosomal S6 kinase alpha antibody, p70 ribosomal S6 kinase beta 1 antibody, p70 S6 kinase alpha antibody, P70 S6 Kinase antibody, p70 S6 kinase alpha 1 antibody, p70 S6 kinase alpha 2 antibody, p70 S6K antibody, p70 S6K-alpha antibody, p70 S6KA antibody, p70 (S6K) alpha antibody, p70 (S6K) -alpha antibody, p70-alpha antibody, p70-S6K 1 antibody, p70-S6K antibody, P70S6K antibody, P70S6K1 antibody, p70S6Kb antibody, PS6K antibody, Ribosomal protein S6 kinase 70kDa polypeptide 1 antibody, Ribosomal protein S6 kinase beta 1 antibody, Ribosomal protein S6 kinase beta-1 antibody, Ribosomal protein S6 kinase I antibody, RPS6KB1 antibody, S6K antibody, S6K-beta-1 antibody, S6K1 antibody, Serine/threonine kinase 14 alpha antibody, Serine/threonine-protein kinase 14A antibody, STK14A antibody

Gene Name

LMF2

Gene ID

91289

UniProt

Q9BU23

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross reactivity with other proteins.

Immunogen

E.coli-derived human LMF2 recombinant protein (Position: E132-A635) . Human LMF2 shares 85.5% and 83.9% amino acid (aa) sequence identity with mouse and rat LMF2, respectively.

Clonality

Polyclonal

Tissue Specificity

Expressed in all tissues.

Applications

Flow Cytometry

Field of Research

Signal Transduction, Signaling Pathway, Small G Proteins

Purification

Immunogen affinity purified.

Form

Liquid

Function

Downstream effector of TOR signaling pathway involved in osmotic stress response. Could be involved in the control of plant growth and development. Phosphorylates the ribosomal proteins P14, P16 and S6. Functions as a repressor of cell proliferation and required for maintenance of chromosome stability and ploidy levels through the RBR1-E2F pathway.

References & Citations

1. Nobuyuki, K. , Shunichiro, S. , Tomoyuki, N. , Kazuya, S. , Nobuto, S. , & Tohru, O. , et al. (2016) . Development of biomarkers based on dna methylation in the ncaph2/lmf2 promoter region for diagnosis of alzheimer's disease and amnesic mild cognitive impairment. Plos One, 11 (1), e0146449. 2. Meant, AntoineGao, BeichenLavoie, GenevieveNourreddine, SamiJung, FloraAubert, LeoTcherkezian, JosephGingras, Anne-ClaudeRoux, Philippe P. (2020) . Proteomic analysis reveals a role for rsk in p120-catenin phosphorylation and melanoma cell-cell adhesion. Molecular & cellular proteomics: MCP, 19 (1) . 3. Swayampakula, M. , Mcdonald, P. C. , Vallejo, M. , Coyaud, E. , & Dedhar, S. . (2017) . The interactome of metabolic enzyme carbonic anhydrase ix reveals novel roles in tumor cell migration and invadopodia/mmp14-mediated invasion. Oncogene, 36 (45), 1-18.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Calculated Molecular Weight

80 kDa

Applications Notes

6

Gene Name Synonym

Serine/threonine-protein kinase AtPK1/AtPK6

Subcellular Location

Cytoplasm. Nucleus.

Protein Name

Serine/threonine-protein kinase AtPK1/AtPK6

Isotype

IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

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